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Tuesday, October 31, 2006

Medical Checklists

What Pilots Can Teach Hospitals About Patient Safety

Published: October 31, 2006

Wearing scrubs and slouching in their chairs, the emergency room staff members, assembled for a patient-safety seminar, largely ignored the hospital’s chief executive while she made her opening remarks. They talked on their cellphones and got up to freshen their coffee or snag another danish.

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Jimmy Turrell

But the room became still and silent when an airline pilot who used to fly F-14 Tomcats for the Navy took the lectern. Handsome, upright and meticulously dressed, the pilot began by recounting how in 1977, a series of human errors caused two Boeing 747s to collide on a foggy runway in the Canary Islands, killing 583 people. Riveted, a surgeon gripped his pen with both hands as if he might break it, an anesthetist stopped maniacally chewing his gum, and a wide-eyed nurse bit her lip.

An attention grabber, yes, but what does an airplane crash have to do with patient safety?

A growing number of health care providers are trying to learn from aviation accidents and, more specifically, from what the airlines have done to prevent them. In the last five years, several major hospitals have hired professional pilots to train their critical-care staff members on how to apply aviation safety principles to their work.

They learn standard cockpit procedures like communication protocols, checklists and crew briefings to improve patient care, if not save patients’ lives. Though health care experts disagree on how to incorporate aviation-based safety measures, few argue about the parallels between the two industries or the value of borrowing the best practices.

Spurred by a 1999 report by the Institute of Medicine, an arm of the National Academies, titled “To Err Is Human,” which estimated that as many as 98,000 patients die annually from preventable medical errors, and by more recent bad publicity from mistakes like amputations of the wrong limbs, many health care providers are redoubling their efforts to improve patient safety.

“We’re where the airline industry was 30 years ago” when a series of fatal mistakes increased scrutiny and provoked change, said Dr. Stephen B. Smith, chief medical officer at the Nebraska Medical Center in Omaha, the teaching hospital for the University of Nebraska.

It is well established that, like airplane crashes, the majority of adverse events in health care are the result of human error, particularly failures in communication, leadership and decision-making.

“The culture in the operating room has always been the surgeon as the captain at the controls with a crew of anesthesiologists, nurses and techs hinting at problems and hoping they will be addressed,” Dr. Smith said. “We need to change the culture so communication is more organized, regimented and collaborative, like what you find now in the cockpit of an airplane.”

After the Canary Islands accident, NASA convened a panel to address aviation safety and came up with a program called Cockpit or Crew Resource Management. The Federal Aviation Administration requires that all pilots for commercial airlines and the military undergo the training. They learn, among other things, to recognize human limitations and the impact of fatigue, to identify and effectively communicate problems, to support and listen to team members, resolve conflicts, develop contingency plans and use all available resources to make decisions.

Recognizing the positive impact of the program on the aviation industry’s safety record, the Institute of Medicine in 2001 recommended similar training for health care workers. The National Academies, the Agency for Healthcare Research and Quality and the Institute for Healthcare Improvement also advocate the training, as well as the use of other aviation-inspired practices like pre- and post-operative briefings, simulator training, checklists, annual competency reviews and incident reporting systems.

The British medical journal BMJ, The Journal of the American Medical Association and The Journal of Critical Care have also published research suggesting that hospitals that adopt these measures have fewer malpractice suits and postsurgical infections. Patient recovery times tend to be lower, and employee satisfaction is higher.

With these endorsements, and with the airline industry cutting salaries, benefits and flight time, many pilots have become part-time health care consultants. For fees that range from $7,000 to $40,000, they offer training and help devise and put in place systemwide safety protocols and procedures. Among the growing number of health care institutions that have hired aviation consultants or adopted aviation safety practices in the last five years are Vanderbilt University Medical Center; Johns Hopkins Medical Institutions; Cedars-Sinai Medical Center in Los Angeles; Vassar Brothers Medical Center in Poughkeepsie, N.Y.; the University of Nebraska; and the University of Texas Medical Branch at Galveston.

“The trend is not surprising given the similarities between health care and aviation,” said Dr. David M. Gaba, associate dean of immersive and simulation-based learning at the Stanford University School of Medicine in Palo Alto, Calif.

“Both involve hours of boredom punctuated by moments of sheer terror,” he said.

In addition to sometimes having to make life-and-death decisions in seconds, pilots and physicians also tend to be highly skilled, Type A personalities, who rely heavily on technology to do their jobs.

Even so, some hospital administrators and experts in human factors argue that aviation safety principles are not wholly transferable to health care. “Medicine is a more complex environment with more professionals interacting than in aviation,” said Robert Helmreich, professor of psychology at the University of Texas at Austin and director of its Human Factors Research Project, which studies team performance and the influence of culture and behavior in aviation and health care.

The definition of an error in health care, Professor Helmreich said, is “fuzzier” than in aviation, where it is easier to identify a “foul-up” and who was responsible. Health care providers’ fear of litigation and losing their medical licenses also hinders the honest reporting of mistakes, whereas aviators are often inoculated against punishment if they promptly report incidents to the authorities. Training programs developed by pilots without knowledge of health care realities can be “appallingly bad,” he said.

More successful are programs developed by consulting firms like LifeWings in Memphis and the Surgical Safety Institute in Tampa, Fla., both of which have professional pilots and physicians developing their training materials and serving on their advisory boards.

Some institutions, like Johns Hopkins, have created their own in-house training programs and safety structures based on aviation. “Aviation provided us with the ideas, which we then modified for health care as well as our particular situation,” said Dr. Peter Pronovost, the director of the Center of Innovation in Quality Patient Care at Johns Hopkins.

Employees who work at hospitals that have adopted these kinds of aviation-based safety programs are mostly enthusiastic. Many say they are more confident doing their jobs thanks to posted checklists, which, for example, include reminders to wash their hands, confirm the identity of the patient and check for drug allergies. They appreciate the fact that they are now not only encouraged to speak up if they are concerned about something, but also required to do so.

“Communication is so much better,” said Shelly Schwedhelm, a nurse and director of perioperative and emergency services at Nebraska Medical Center, which instituted aviation-style safety measures a year ago.

“We now have debriefings after every surgery, during which we identify what we could do better but also what went right,” she said. “I’m hearing compliments and acknowledgment, which has really boosted morale.”

Still, some doctors balk at the rote quality of the procedures, claiming that they are unnecessary and undermine their authority.

“I had one surgeon tell me that checklists are for the lame and weak,” said Professor Helmreich of the University of Texas.

Even the most recalcitrant tend to come around, however, when a safety check catches one of their mistakes, possibly saving a patient and preventing a malpractice suit.

“I’m seeing errors caught virtually every day” in the operating room, said Dr. Timothy Dowd, the chairman of the anesthesiology department at Vassar Brothers, where critical-care staff members underwent aviation-based patient-safety training six months ago.

“Even the most curmudgeonly surgeon has to admit this is a better way,” he said.



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Monday, October 30, 2006

Honey Bees & Evolution


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Honeybee Genome May Shed Light on Social Evolution

By David Brown
Washington Post Staff Writer
Monday, October 30, 2006; A06

Bees and people have a lot in common.

We both live in groups and snuggle with others when cold. We both know that staying clean helps prevent disease. We both prepare food for others and leave home to get it even when we aren't hungry. We both can communicate through dancing.

Of course, there are differences.

Bees are an inch long. They copulate while flying. Each winter, the females kick the males out of the house to die.

So to what extent do genes explain our two wildly different evolutionary journeys? Biologists now have a better way of exploring that question, and a whole lot of other ones.

Last week, the Honeybee Genome Sequencing Consortium announced that it had finished copying out the genetic message of Apis mellifera , the world's most important pollinator, maker of nature's best-known sweet food, and object of human fascination and delight for eons. The honeybee becomes the third insect to have its genome fully transcribed, preceded by the fruit fly drosophila and the malaria mosquito anopheles. A flour-eating beetle, an aphid and a wasp are next in line.

The work was done by 150 people in about 20 countries over the past three years. The huge mass of data -- along with that from the other species -- will help sketch a picture of what it means to be an insect, as well as what it means to be a honeybee.

Insects are the most diverse group of animals on Earth, with about 925,000 identified species. The genetic exploration may eventually shed light on the biology of togetherness and cooperation, which bees and people both discovered in the 600 million years since they last shared a common ancestor.

"We can use this genome to go looking for any and every gene that might be involved in the evolution of sociality. But that is down the road," said Hugh M. Robertson, an entomologist at the University of Illinois at Urbana-Champaign.

In a long paper in the journal Nature and several shorter ones in Science, Robertson and his colleagues describe their initial insights on the honeybee genome, which is full of both surprises and confirmed hunches.

The honeybee has 10,000 to 15,000 genes arrayed on 16 chromosomes, compared with humans' estimated 24,000 genes and 24 chromosomes (22 regular ones and two sex chromosomes). Comparisons with the fruit-fly and mosquito genomes suggest that bees evolved more slowly than either of those other insects. Curiously, some bee genes -- notably the ones responsible for internal "clocks" and circadian rhythms -- are more similar to mammals' genes than flies'.

But the most interesting insights so far come from discoveries of what parts of the bee's genome have been enriched, ignored or discarded by the evolutionary force of natural selection.

Compared with other insects, honeybees have only one-third as many genes involved in recognizing and killing their microbial enemies. This is a surprise for an organism that spends 95 percent of its life in a crowded, moist 94-degree indoor environment hospitable to bacteria and parasites.

But bees are extremely hygienic and prevention-minded. When a developing larva dies, it is removed from its cell in the honeycomb immediately and the carcass is flown a distance from the hive before it is discarded. Nurse bees secrete antimicrobial substances into the food they provide the larvae. Honey, the principal source of food over the winter, does not support microbial growth because of its high-sugar, low-water makeup. Overall, it appears that compared with those of other insects, a bee's genome is less concerned with protecting the individual from disease and more concerned with protecting a larger organism -- the entire colony.

Bees also have fewer genes encoding the proteins that make up their exoskeleton. The researchers speculated that is because they spend their larval stage and much of their early adulthood inside the hive, protected from ultraviolet light and temperature stresses.

But what is lost in the immune system and the skin is gained in the bee equivalent of the nose.

A. mellifera has 170 genes for "odorant receptors," of which 157 are in a gene family so far found only in honeybees. This is far more smelling apparatus than either fruit flies (with 62 receptor genes) or mosquitoes (with 79) possess. It probably reflects the extreme importance of smell in helping bees find flowers and communicate with one another, including with their queen, through pheromones.

At the same time, honeybees have a paucity of taste receptors -- 10, compared with the fruit fly's 68 and the mosquito's 76.

Over the eons, taste has evolved primarily as a mechanism of defense. Plants evolve toxins to protect themselves from being eaten; animals evolve receptors to detect the toxins. (This is part of the reason human beings have far more bitter than sweet receptors, bitter being the taste of poisonous plant alkaloids.) Bees, however, have a far more congenial relationship with the plant world. They pollinate the plants and the plants feed them.

"Honeybees for a long time have not needed a lot of gustatory receptors because they have not been in a chemical arms race with plants," Robertson said. He added that an unanticipated, but entirely logical, discovery in the bee genome supports this theory. Compared with other insects, A. mellifera has only half the number of genes encoding the enzymes that detoxify dangerous compounds.

But there is no genomic smoking gun that explains the species' most remarkable behavior -- the ability of bees to tell one another the location of food sources outside the hive through a ritualized "dance" that uses the sun's position as a point of reference. There is no cluster of brain genes possessed only by bees.

"It's not what you have in your genome but how you use it" that must explain that capacity to learn and communicate, said Jay D. Evans, a scientist at the U.S. Department of Agriculture's Bee Research Laboratory in Beltsville. That is also probably the reason chimpanzees and human beings are so different in cognitive ability despite having 97 percent identical genes, he added.

One line of research the completed genome will help advance is which genes constituted the raw material that through natural selection allowed cooperative behavior to emerge in honeybees.

Work already done by Gene E. Robinson, a neurobiologist at Urbana-Champaign and a co-leader of the genome consortium, and by Gro Amdam and Robert E. Page Jr. at Arizona State University, suggests that reproduction and nutrition genes evolved greatly in honeybees.

"Food and sex -- it is not unreasonable to hypothesize they were important in the development of social behavior," Robinson said.

© 2006 The Washington Post Company


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Sunday, October 29, 2006

Timely Idea

the undercover economist: The economic mysteries of daily life.

EST. CST. MST. PST. NOT!Would the United States be better off with only one time zone?


The clocks go back tomorrow, which means an extra, delicious, guiltless hour in bed. Every year I dream of a world where the clocks go back every day. Of course, that would create trouble, notably that in two weeks' time I'd be waking up after sunset. So, I toe the line and put the clocks back only once a year, and—sigh—put them forward again in the spring.

My annual inner monologue suggests two reasons to get up in the morning and go to bed at night: first, to enjoy the sunshine, and second, because that is what everybody else does. But what if the two imperatives collide? What matters more, waking up at the same time as everyone else or waking up with the sun? It might sound like a daft question, but not if you're a Hong Kong-based journalist filing for a London-based newspaper or a financial analyst in Silicon Valley who needs to be awake when the market opens on Wall Street at 6.30 a.m. Pacific Time.

Coordination may be important not just for the global elite, but also for those who deal with them. If enough California financiers are going to work at 5:00 in the morning, the gas stations and coffee shops will start to open early, too: The baristas there don't need to coordinate with the baristas in Manhattan, but the financiers provide a link that is powerful enough to make sure that they do anyway.



Any resident of Queensland in Australia can assure you of this. Queensland doesn't switch to daylight-saving time when the other east-coast states do, but some Queenslanders simply get out of bed earlier in the winter to stay in sync. Or consider the states in northern Mexico, which align their time zones with the neighboring U.S. states rather than the rest of the country, even down to the idiosyncrasies of whether daylight-saving time is observed.

All that creates a problem. Not every Queensland resident synchronizes with the rest of the country, which means that neighbors will be out of sync with each other. The Californian demands that the barista rises early, which might also lead to demands for early rising by the barista's wife, bus driver, nanny, or mailman. Perhaps it would be better for the United States and Australia to mimic China in having a single, unified time zone. That would get everybody in sync with each other, although not with the daylight. So, which is more important—coordination or sunlight?

Three economists, Daniel Hamermesh, Caitlin Myers, and Mark Pocock, have devised a way to find out how important these coordination effects really are relative to sunrise or to the official time. One of their tools is based on a historical relic: the fact that television schedules in the United States vary by time zone.

This practice originated in the 1920s, when the Eastern and Central time zones received simultaneous live radio broadcasts, with the Central time zone broadcast being an hour earlier on the clock. The sparsely populated Mountain and Pacific time zones had to listen to repeats instead. For no other reason than pure tradition, then, prime-time evening shows screen at 10 p.m. Eastern and Pacific, 9 p.m. Central and Mountain.

But then, take a state such as Arizona, which does not observe daylight-saving time. (Neither does the adjacent Mexican state of Sonora—more coordination.) In summer, Arizona is in the Mountain time zone; in winter, it is in the Pacific time zone but with the evening shows still at Mountain times. That sort of quirky setup—there are others—allows Hamermesh and his colleagues to show the impact of the television schedules on people's daily routines.

Rather depressingly, David Letterman outshines the sun in his effect on what people are doing. Push the television schedules an hour later and 5 percent of people will be watching television later—nearly a third of those actually watching the television. But if sunset is an hour later (because the individual is at the western end of a time zone), only half of 1 percent of people will watch later television. The effect also spills over onto sleeping patterns: The television, more than the sunrise, determines when people get up in the morning.

That itself simply shows that people pay more attention to the television than to the great outdoors. But there is also a strong signal that coordination really matters, because the television schedules govern the behavior even of people who don't watch television. Even those people who don't know who David Letterman is live their lives to his schedule so that they can synchronize with a nation of TV-watchers. Perhaps the Chinese are right: Forget the sunrise and make sure, instead, that people are in sync with each other.

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Tim Harford is a columnist for the Financial Times. His latest book is The Undercover Economist.
Photograph of clock on Slate's home page courtesy of Photodisc/Getty Images.
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Thursday, October 26, 2006

Best defense against the flu

Our best hope during the next flu epidemic. Be forewarned.

Op-Ed Contributor

Face Facts

Published: October 25, 2006

Stanford, Calif.

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Jennifer Daniel

DESPITE all the attention given to anthrax and smallpox and potential weapons of mass destruction, pandemic influenza is probably the world’s most serious near-term public health threat. If a strain similar in effect to the 1918 Spanish flu (which killed tens of millions of people worldwide) emerges in the next several years, it is highly likely that an effective vaccine will not be available during the pandemic’s first wave, that we won’t have enough antiviral drugs for large-scale prophylactic use, and that hospitals will be too overwhelmed to treat most cases.

Consequently, as in 1918, we will need to combine medical efforts with voluntary and forced social changes — closing schools and churches, canceling public gatherings, keeping workers at home — to hinder the flu’s spread. Our government must draw up a plan for educating the public about effective nonpharmaceutical interventions like hand washing and face protection like masks.

A prerequisite for doing so is determining the biggest culprit in spreading influenza: droplet transmission, in which an infected person sneezes or coughs directly into the mouth, nose or eyes of someone who is susceptible); contact transmission, in which virus is transferred via hands either directly, say, through a handshake, or indirectly through an object like a doorknob; and aerosol transmission, in which evaporated virus-containing particles are inhaled.

Remarkably, this issue has not been resolved: the Department of Health and Human Services’ Pandemic Influenza Plan states that “the relative clinical importance of each of these modes of transmission is not known.” As a result, the government enthusiastically endorses frequent hand washing — which would reduce contact transmission, and costs nothing — but remains noncommittal about face protection. While the government says that it might be beneficial, it doesn’t make respirators or masks available. Yet face protection would guard against aerosol and droplet transmission, and even reduce contact transmission by making it difficult to place fingers into one’s mouth or nose.

A Stanford graduate student, Michael Atkinson, and I recently performed a detailed study of the routes of transmission, using data on influenza and on rhinovirus, which causes the common cold. Our findings suggest that the dominant mode of transmission for influenza is aerosol — implying that hand washing will make little difference. This is consistent with the views of leading researchers several decades ago, views that have somehow been forgotten by the public health community.

We found that ventilation, like placing a fan in an open window, and humidifiers (most influenza strains survive in the air for much less time when the humidity is raised to about 65 percent) can reduce transmission slightly. Sleeping in separate bedrooms (and working in separate offices) can help even more.

But the single most effective intervention is face protection. And because roughly one-third of influenza transmissions occur before an infected person exhibits symptoms, these precautions should be taken whenever people are in the same room throughout the pandemic period.

There are two kinds of face protection: N95 respirators, as worn by construction workers, for instance, and surgical masks of the sort worn by dental hygienists. (The respirators cost roughly a dollar apiece, the surgical masks 10 cents.) Their efficacy in preventing aerosol transmission depends on three factors: the extent to which the face filter prevents virus particles from passing through, how tightly the device fits and — most important — how long people can be coerced into wearing them.

To our surprise, we found that the filters in surgical masks, although not as good as the filters in N95 respirators, are still quite effective. And although a surgical mask fits much more loosely and allows more leakage, it’s also more comfortable — and therefore likely to be effective because it’s used more. Wearing nylon hosiery over a surgical mask essentially eliminates the face leakage, making this combination a practical, albeit macabre, alternative. The less comfortable N95 respirators would probably result in lower compliance.

The government doesn’t stockpile masks and respirators, and the manufacturers aren’t able to produce a huge number of them quickly. But the way forward seems clear: the government needs to build up a supply of respirators and masks just as it does with vaccines and antivirals. It should first hire a whiz-bang design company to create, within one month, a surgical mask that comfortably adheres to the face, and then decide on the appropriate mix of respirators and masks. Next, it needs to sign contracts with manufacturers to stockpile masks and respirators, relieving the manufacturers of liability issues.

Although there is very little technological risk involved (masks and respirators are easier to make and safer to use than vaccines), several issues need to be ironed out. First, the effectiveness of N95 respirators and masks varies widely. The government needs to educate the public (the brands are anonymous in the published studies) and should stockpile only the most effective brands.

Also, if respirators and masks are discarded daily, as they are in many hospitals, the national demand during a three-month pandemic could be 10 to 20 billion, and the cost for respirators for a family of four several hundred dollars. Such waste isn’t necessary. The virus does not survive longer than a few hours on the material used for masks and respirators, so they should be re-used until they disintegrate.

The government and the public health community must switch mindsets, from the current perspective of protecting workers paid to do a dangerous job everyday, to that of providing citizens with the tools to best protect themselves during a pandemic.

It may take 18 months to build a stockpile of respirators and masks, so there is no time to lose. The American people’s faith in their government will be seriously undermined if, along with larger measures like school closings, it cannot provide effective face protection for its citizens during a deadly pandemic. Masks and respirators may be our main lines of defense during a pandemic.

Lawrence M. Wein is a professor at Stanford’s graduate school of business.



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Wednesday, October 25, 2006

Health Care for the Poor

Hospitals Try Free Basic Care for Uninsured

Published: October 25, 2006

AUSTIN, Tex. — Unable to afford health insurance, Dee Dee Dodd had for years been mixing occasional doctor visits with clumsy efforts to self-manage her insulin-dependent diabetes, getting sicker all the while.

Erich Schlegel for The New York Times

Natavidad Martinez, who has liver cancer, was awarded disability payments but lost her Medicaid coverage.

Multimedia

The UninsuredGraphic

The Uninsured

Erich Schlegel for The New York Times

With preventive efforts, the cost of care for Dee Dee Dodd, a diabetic, was cut nearly in half in 18 months.

In one 18-month period, Ms. Dodd, 38, was rushed almost monthly to the emergency room, spent weeks in the intensive care unit and accumulated more than $191,000 in unpaid bills.

That is when nurses at the Seton Family of Hospitals tagged her as a “frequent flier,” a repeat visitor whose ailments — and expenses — might be curbed with more regular care. The hospital began offering her free primary care through its charity program.

With the number of uninsured people in the United States reaching a record 46.6 million last year, up by 7 million from 2000, Seton is one of a small number of hospital systems around the country to have done the math and acted on it. Officials decided that for many patients with chronic diseases, it would be cheaper to provide free preventive care than to absorb the high cost of repeated emergencies.

With patients like Ms. Dodd, “they can have better care and we can reduce the costs for the hospital,” said Dr. Melissa Smith, medical director of three community health centers run by Seton, a Roman Catholic hospital network that uses its profits and donations to provide nearly free care to 5,000 of the working poor. Over the last 18 months, Ms. Dodd’s health has improved, and her medical bills have been cut nearly in half.

Reaching out to uninsured patients, especially those with chronic conditions like diabetes, hypertension, congestive heart failure or asthma, is a recent tactic of “a handful of visionary hospital systems around the country,” said Karen Davis, president of the Commonwealth Fund, a foundation in New York that concentrates on health care. These institutions are searching for ways to fend off disease and large debts by bringing uninsured visitors into continuing basic care.

The public hospital systems in New York and Denver, for example, have both worked to steer uninsured patients to community clinics, charging modest fees, if any. New York’s public system, the Health and Hospitals Corporation, has assigned some 240,000 uninsured patients to personal primary care doctors. A computerized system tracks those with chronic conditions, and when necessary, social workers contact patients to make sure they get checkups and follow medical advice.

“For most preventive efforts there is an upfront expense,” said Alan D. Aviles, president of the corporation. “But over the long term it saves money.”

Denver’s public system, Denver Health, has 41,000 uninsured patients enrolled in its clinics. Officials there calculate that for every dollar they spend on prenatal care for uninsured women, they save more than $7 in newborn and child care.

The “safety net” plan of the Seton system in Central Texas accepts people making 150 percent to 250 percent of the federal poverty limit and has resources to support 5,000 patients. (People below the poverty line, which is $13,200 a year for a family of two in the contiguous states, can obtain care through the public clinic system.)

Officials scrutinize the records of plan members to see who is still overusing the emergency room or being repeatedly hospitalized — these high-cost patients total some 40 each month — then assign them caseworkers to help improve care and bring down costs.

A special effort to educate 631 asthma patients saved the plan $475,000 in one year, Seton officials said.

In a more unusual step, Seton officials also look for frequent emergency room users who do not qualify for the hospital’s charity plan because they live in a different county, like Ms. Dodd, or have incomes just above the threshold. In a dozen cases so far, all involving diabetics, a committee has judged that it makes financial sense to bring these people into the charity plan anyway and provide intensive support.

Other answers to the insurance crisis are being tried around the country, including the creation of subsidized, bare-bones policies for small businesses. Vermont, Maine and especially Massachusetts are using combinations of state and federal money and employer mandates to extend insurance.

Still, only a fraction of the uninsured, in Central Texas and in most other states, are benefiting.

“All these local efforts are commendable, but they are like sticking fingers in the dikes,” Ms. Davis of the Commonwealth Fund said, noting that the larger trend was hospitals’ seeking to avoid the uninsured.

Nowhere is the problem more acute than in Texas, where nearly a quarter of the population is uninsured, the nation’s highest rate. Small businesses here are unlikely to offer benefits, and the state government’s unusually stringent restrictions on Medicaid for adults leave many of the working poor at risk.

Even without counting the large immigrant population, Texas has the country’s highest share of uninsured, at 21 percent, according to the Center for Public Policy Priorities in Austin.

“All the hospitals here provide some uncompensated care, and they are eating it and passing the costs along to the payers,” said Patricia A. Young Brown, president of the Travis County Healthcare District, which was set up last year to oversee care of the indigent through public clinics, drawing on property taxes to pay.

“So insurance rates go up, and then more businesses drop insurance,” Ms. Young Brown continued, describing a trend unfolding nationwide. “It’s hard to see where it will end. We hear a cry for national and state leadership.”

The private People’s Community Clinic, supported in part by the St. David’s Hospital system, gives primary care to 11,000 people in Austin who are uninsured or on Medicaid and related programs.

“I think we are a good Band-Aid for those able to come to our clinic,” Regina Rogoff, director of the clinic, said. “But it’s not a solution to have such a ragtag, makeshift system.”

Austin hospitals and charity clinics have also joined in a pioneering data-sharing system to track visits by uninsured patients and fight unnecessary use of the emergency room. But rural counties in Texas offer little aid, and rural residents with serious maladies end up traveling to urban emergency rooms.

The current patchwork also pits different levels of government against each other.

Natavidad Martinez, 51, who used to work as a bookbinder for $7 an hour and never had insurance, has found herself in a bureaucratic nightmare.

In March 2005, Ms. Martinez, a Seton patient, was found to have liver cancer. She was put on Medicaid, applied for federal disability and was put in line for a liver transplant, without which, doctors said, she had six months to two years to live. Through the summer of 2005, she made the hour-and-a-half drive from her home to San Antonio for preparatory tests.

That August, she was awarded disability payments of $561 a month. But because her income surpassed the $535 limit for Medicaid in her circumstances, she said, she was told by the state that her coverage had ended, and the hospital said it could not proceed with a transplant.

“I asked Social Security if they couldn’t just reduce my payments by $30 a month,” she said, “but they said it doesn’t work that way.”

In another twist, by federal rules, she will qualify for Medicare two years after the initial finding of disability. She awaits the start of Medicare coverage next March, when she can rejoin the transplant line.

In Texas, as throughout the country, the coverage of poor children through Medicaid and related programs expanded greatly over the last decade. But a majority of states do not provide Medicaid to parents making even poverty-line incomes, and Texas is one of the least generous: here, a working parent of two does not qualify for coverage if he or she makes more than $3,696 in a year, leaving people like Ms. Dodd to fend for themselves.

Ms. Dodd, who worked as a dental assistant, is married to a truck driver, has four children and lives on a country road in Hays County, south of Austin. Ten years ago, after her weight fell to 82 pounds, she learned that she was a “brittle diabetic,” subject to rapid and dangerous changes in blood sugar. She saw a doctor only sporadically because visits cost $120 — money she did not have.

“I had to stop working, so then I couldn’t afford to go to the doctor, and then I had to go to the emergency room,” Ms. Dodd said.

She was having repeated episodes of ketoacidosis, a chemical imbalance that sometimes put her into life-threatening comas. Years of poor care had weakened her and led to side effects like esophogeal ulcers that could probably have been prevented, her doctors said.

Ms. Dodd still has problems, but the use of a $3,200 insulin pump paid for by Seton, which automatically adjusts her insulin levels, along with access to an endocrinologist and home counseling have reduced their severity. Her care in the last 18 months has cost Seton $104,697, far below the $191,277 for the previous period. More important, the later figures include less hospital time and more medicines and expert advice.

“The money we save,” Dr. Smith, of Seton, said, “money that is not hemorrhaging through the I.C.U., is money we can do so much more with to help her upfront.”



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Tuesday, October 24, 2006

The Sea

Fishing With Carl Safina

The Biologist and the Sea: Lessons in Marine-Life Restoration

Scott Eckert

Fusing passions Carl Safina — with a leatherback turtle in Trinidad.

Published: October 24, 2006

MONTAUK, N.Y. — For Carl Safina — a biologist, conservationist and prize-winning author — passions and intellectual pursuits are deeply entwined.

Multimedia

Readers’ Opinions

Forum: The Environment

Bastienne Schmidt for The New York Times

Carl Safina, in Montauk, says he wants to develop a “sea ethic.”

The best place to observe this fusion is aboard his 24-foot powerboat First Light at the time of day for which it is named, when Dr. Safina is scanning flocks of terns hovering over the tide-roiled waters between Montauk, the tip of Long Island, and the slate-dark hump of Block Island to the east.

Dr. Safina’s doctoral thesis was on the interrelated behaviors and annual rhythms of the common tern and bluefish, which feast on the same bay anchovies and other small prey.

On many days, though, he is carefully tracking the birds not in pursuit of new knowledge, but in hope they will point him to dinner.

On a recent three-hour fishing trip, in snippets of windblown conversation while steering his boat, jigging or casting, then fighting, landing and cleaning fish, Dr. Safina reflected on two decades of work revealing the enormous disruption of ocean ecosystems by industrial-scale fishing and other human activities.

Now 51, he has written three books on the rising human impact on seas once presumed boundless. The first was on fishing, the next on the travels and travails of albatrosses. His latest, “Voyage of the Turtle: In Pursuit of the Earth’s Last Dinosaur” (Henry Holt, 2006), follows the struggles of the ocean’s ancient leatherbacks and other sea turtles.

His prime goal, he has said, is to develop a “sea ethic” similar to the land ethic of Aldo Leopold, and a scattering of success stories has convinced him that a balance is still possible between exploitation and conservation of marine resources.

On this day, several bluefish were hooked and two were landed as he zigzagged over the North Rips, a series of shallow ridges that, like Long Island and Block Island, are deposits of sand and gravel left behind after the great ice sheets of the last ice age stopped their southward advance.

The next stop was Treasure Holes, dimples in the sea floor favored by fluke, a hefty, toothsome flatfish prized for both its fight and its flavor.

He hooked a heavy fluke and reeled it toward the surface.

Q. O.K. if I net him?

(The large brown, speckled fish flopped onto the deck, and Dr. Safina grabbed a yardstick to see if it topped the 18-inch limit.)

A. For this one I would say you don’t really need the ruler. He’s about 21 inches. These fish were very depleted about 10 years ago, and they’ve been recovering. The minimum size has been raised several times, so I kind of feel O.K. about taking a couple of these for the table. In general, I’m O.K. with using what’s in the oceans. I just don’t think we should be using it up. So the point to me is not necessarily to put things off limits, although some places probably should be off limits where fish spawn and places like that. But the main thing is to restore the abundance of what’s in the ocean so that we can have a viable system where all these animals can live and eat each other, and then we can take a little bit.

Q. There are all these sexy critters in the ocean — sharks, whales — and then along come these things called sea turtles. Why did you choose to focus a couple of years of your life and a book on sea turtles?

A. Well, actually, I was writing my book on albatrosses, and I saw sea turtles laying eggs for the first time. I had seen them in the ocean a number of times, and they always struck me as extremely graceful and just really lovely. There is something about the magisterial slowness of their movements, and many of them get to be rather old, so they seem like venerable citizens of the deep.

But seeing the turtle lay eggs was also a very moving experience, and I thought that it would be nice to follow them around, write a book about how the oceans are changing sort of through the eyes of sea turtles.

Q. What most discourages you related to the trends you see in the oceans?

A. That it’s so easy to see what we need to do, it’s so easy to see how things can be so much better and yet it’s taking so much time to come around to it.

Q. What are some of those improvements?

A. We need to just set fishing quotas and adhere to them, and make them realistic, and listen to what the scientists say about how many fish can come out of the ocean. And if we do that, we will get more of what we want.

Q. Why do you think scientists don’t tend to be listened to very much?

A. Because usually people are very greedy and try to cheat. Everybody tries to get the most of what they can before everybody else gets to it.

Q. And what’s one of the most encouraging things you’ve seen?

A. That fish are recoverable. Many of the fish that we have here were much less abundant 15 years ago than they are now. We did get some good regulations passed, and the fish began recovering right away. They know what to do. If you just don’t kill them as fast, they start coming back. So the most encouraging thing is that it works, but a lot of that could be much more widespread throughout the country and the rest of the world.

Q. One thing that seems to be encouraging about the way the oceans behave is you tend to fish something to commercial extinction long before it’s actually gone forever. Do you think that’s true, and is that why there is this sense of always being able to go back to the well?

A. I saw a photograph the other night in a book on extinction of the last bear in Switzerland. There were about 50 people surrounding this thing, and you know they had been trying very hard to kill the last bear. It was about 100 years ago. But in the ocean, things get very rare and then it becomes in most cases not economically profitable to keep after them, so the fishery tends to go out of business before they completely extinguish the last fish.

There are exceptions to that. There are some populations of cod that seem to have been fished out of existence. They no longer spawn in those areas. Those individual populations seem gone. But for the most part, because we’re not so much building structures in the ocean, the habitat is still there. When we leave before the last fish is caught because we are not making money, there is usually this little reservoir of recovery potential. And also fish tend to have a very high rate of fecundity; they lay millions of eggs. If the bulk of the habitat is there and the pressure comes off a little bit, they usually can rebuild much faster than some other kinds of animals.

We’ve seen that with a lot of these species here, including these fluke that we’re fishing for at the moment. Striped bass is a fantastic recovery, another fish that we love to catch locally. In the mid-1980’s we were talking about putting them on the endangered species list. Black sea bass are recovering.

That makes me very hopeful that we can actually solve a lot of these problems on a bigger scale and for the long term.

Q. What’s the farthest afield from here you’ve ever fished, the most exotic, unusual, different place?

A. I did a little bit of fishing in Palau, a little in Alaska. But you know when I’m in really exotic places far from home I tend not to really want to go fishing. I like seeing wildlife and things like that. But I really don’t like fishing so much if I don’t understand the area or why we’re in a certain spot.

What I like is really understanding where to look for the fish, what to do to try to catch them, a sense of the season, what it was like last week, what it was like at this time last year or 10 years ago. The context really means a lot to me. So a lot of what I like about fishing goes away if I’m far from home.

Q. What’s the best thing about fishing?

A. Well, it’s called recreation, and I think of that as re-creation. It does get you back in touch with a lot of the things that have to do with who we are, and my love of being outdoors, my love of nature, all those things. Sometimes I have other things to do that are a lot more important, and I put this off and I just sort of downgrade the importance of coming out here. Then, when I get out here, it’s like, “Oh, that’s right,” how nice this is, how relaxing, how rejuvenating, how original it seems to feel.



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Monday, October 23, 2006

Menstrual Cycles ended forever

medical examiner: Health and medicine explained.

Girl TalkA new pill that stops your period.


If a new brand of birth control gets approved early next year, that time of the month could become the time of, like, the decade. Lybrel, a birth-control pill made by Wyeth, would be the first oral contraceptive to deliver an uninterrupted supply of hormones. Seventy percent of women who took it for six months were period-free, according to a preliminary study by the company.

Wyeth isn't the first pharmaceutical company to reimagine the menstrual cycle. In 1992, the FDA approved Depo-Provera, an injection that is repeated every three months. In 2003, Seasonale rescheduled the monthly period to four times a year. And in July, the government gave the go-ahead for Implanon, an implant that delivers a steady hormone stream for up to three years. But the pill is the favorite means of birth control of the nearly quarter of American women of childbearing age who take hormonal contraceptives. That means Lybrel—and the other brands that will surely follow—could change the menstrual cycle as we know it. The appeal is obvious: No more bloating, cramping, food cravings, and PMS jokes, not to mention the savings in unpurchased tampons and such. But in the end, for reasons both medical and cultural, it's not clear that putting the kibosh on the curse is a good idea.

Traditional pill packs contain a week of placebos for each monthly cycle, and, as a result, women who take them appear to menstruate. But it turns out that the bleeding serves no reproductive purpose. Since there's no egg to flush out, the bleeding is a symptom of withdrawal from progestin and estrogen, the hormones in the pill—in essence, it's a fake period. The inventors of the pill, which debuted in 1960, supposedly decided to mimic the menstrual cycle because they thought that would make women more psychologically comfortable with the product.



Western women today are estimated to average about 400 menstrual cycles over the course of their lifetimes. Pregnancy and nursing halt periods for a time, of course. And for years physicians have informally advised women with painful periods to practice "menstrual suppression" by taking hormonal contraceptives continuously. Birth-control medications tend to lessen menstrual and premenstrual symptoms to begin with, and some studies show that fewer periods may mean even more relief.

Now Lybrel is explicitly selling all of this, by prescription, at a drug store near you. Women can shut off their systems for law school, a trip around the world—even their entire 20s. Random spotting is common while using Lybrel, especially at the start. But in a study of another brand called Alesse, 90 percent of participants did not bleed at all after a year of use, according to Leslie Miller, associate professor of obstetrics and gynecology at the University of Washington. "We can manipulate menstruation," she says.

Life without getting your period, though, would be life without one of the touchstones of the female experience: a sisterhood of shared empathy, tampons and chocolate, and laundry lessons passed from grandmother to granddaughter. Liberation from premenstrual emotional peaks and valleys sounds great, but we would also lose the surge of creativity and libido that comes with the urge to strangle your houseplants. Would movies be as poignant, or garlic mashed potatoes ever taste as good?

In two different surveys of college women, Ingrid Johnston-Robledo, associate professor of psychology and women's studies at the State University of New York, College at Fredonia, found that women who were asked to name positive aspects of menstruation reported that it was a sign of health and fertility and that it helped connect them to other women and the rhythms of nature.* This may sound like an ode to the inner moon goddess, but it has relevance. Johnston-Robledo found that women who didn't like their periods were also more ashamed of their bodies.

At the same time, there may be some medical arguments for suppressing one's period, at least for a limited period of time. Hormonal contraceptives are known to decrease the risk of ovarian and endometrial cancers, so some doctors think a continual dose of the pill would further reduce those risks. No blood loss also means less anemia. And then there is the provocative argument of Brazilian gynecologist Elsimar Coutinho. In his 1999 book Is Menstruation Obsolete? he writes that modern women experience "incessant ovulation," in contrast to our ancestors, who started menarche later and had many fewer periods because they gave birth and breastfed far more frequently. Women's bodies may not have evolved to handle so many periods and would appreciate a break, Coutinho thinks. (co-authored with Sheldon J. Segal),

But if modern menstruation isn't completely natural, by prehistoric standards, suppressing one's period by taking hormones is even less so. No one knows the health effects for menstruating women of long-term continuous exposure, especially the risks of blood clots and breast cancer and the effect on later fertility. The uncertainties are especially troubling for adolescents whose reproductive systems continue to develop after they start menstruating, explains Jerilynn Prior, director of the Centre for Menstrual Cycle and Ovulation Research in British Columbia. Nearly one in five teens uses a form of hormonal birth control. Given the unknowns, perhaps doctors should consider setting a minimum age requirement for Lybrel, or limiting how long women can stay on it.

Nor is the pharmaceutical industry's track record on birth control exactly reassuring in weighing the risks and benefits. In 2002, the implant Norplant was pulled from the market after questions about its effectiveness and lawsuits by women claiming they were not adequately warned of side effects. In 2004, the FDA required that Depo-Provera include a label warning of risk to bone density. And last year, the FDA warned that the high levels of estrogen found in the Ortho-Evra patch increased the risk of blood clots after about a dozen young women died from clotting believed to be related to it. Maybe Lybrel will prove to be a dream drug with none of these problems; at the moment, we don't have the data to know. Periods, on the other hand, are time-tested. They tell you that you're not pregnant, and they're a sign that your body is working as it should. That's worth some fuss.

Correction, Oct. 23, 2006: The original sentence slightly misstated the name of State University of New York, College at Fredonia. (Return to the corrected sentence.)

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Sarah E. Richards is a freelance writer based in New York City. She can be reached at sarah@saraherichards.com. Photograph of a woman on Slate's home page by Ja

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